One-in-a-million people are living with EHE worldwide.

Our mission is to find treatments and a cure for epithelioid hemangioendothelioma (EHE) by advancing research and driving collaboration among patients, researchers, and clinicians.

We envision a world where Epithelioid Hemangioendothelioma (EHE) is easily diagnosed and treatable. Join our dedicated community by subscribing to our emails.

Patient-Powered EHE Research

EHE Biobank

Patients are the key to finding new treatments for EHE! Researchers need tumor tissue and fluid from EHE patients to understand disease progression and speed the development of new drugs and therapies.

EHE Global Patient Registry

The EHE Global Patient Registry empowers people with Epithelioid Hemangioendothelioma (EHE) to join together to improve our understanding of this ultra-rare sarcoma. We need every EHE patient to join this critical tool used to support researchers searching for treatments and a cure for EHE.

Latest EHE News, Events and Research

Across Borders and Histologies: Rethinking Endpoints for Vascular Sarcoma Trials

By Kristianne Oristian, PhD | April 8, 2026

We recently shared the results of a phase 2 study that evaluated the drug eribulin in two vascular sarcomas, angiosarcoma and EHE. To accompany this work, Dr. Tom Chen of National Taiwan University College of Medicine has shared important commentary in Clinical Cancer Research, highlighting the importance of interpreting data in a disease-specific manner and […]

EHE Foundation Awards $335,000 in New Research Grants to Advance Progress in EHE

By EHE Foundation | March 16, 2026

The EHE Foundation is proud to announce $335,000 in funding through the 2026 EHE Foundation Research Grants Program to support two innovative research projects in epithelioid hemangioendothelioma (EHE). Selected for their scientific merit, potential impact, and clinical relevance, these projects address two important priorities in EHE research: biomarker development and new therapeutic approaches. Together, they […]

The Pledge: Edition 43, Q4 – October-December, 2025

By EHE Foundation | February 15, 2026

Publication of The Pledge quarterly newsletter is led by the EHE Rare Cancer Charity (UK). EHE patient advocacy groups from around the globe provide content, including research news, patient and fundraising stories, and much more. Click here to view the most recent edition of the online EHE newsletter, The Pledge.

Understanding Quality of Life for People Living With EHE

By Kristianne Oristian, PhD | February 10, 2026

The European Organisation of Research and Treatment of Cancer (EORTC) is conducting research to better understand health-related quality of life (HRQoL) concerns among people living with rare cancers. Recently, researchers analyzed results from a group of 31 people with EHE from 11 different countries who participated in the study. The findings showed that pain–and the […]

Exploring Eribulin as a Potential Treatment Option for EHE

By Kristianne Oristian, PhD | February 10, 2026

Prior research has shown that a class of medications called microtubule inhibitors may be effective at controlling the growth of EHE tumors. Recently, researchers conducted a phase 2 study to test whether the microtubule inhibitor eribulin is a safe and effective way to treat patients whose tumors continued to grow after prior treatment. Six (6) […]

EHE Foundation Welcomes Two Leading Sarcoma Experts to Its Scientific & Medical Advisory Board

By EHE Foundation | February 8, 2026

EHE Foundation is pleased to announce the appointment of two distinguished physician-scientists to its Scientific & Medical Advisory Board: Nam Quoc Bui, MD, and Benjamin A. Nacev, MD, PhD. Their expertise in sarcoma medical oncology and translational research will greatly strengthen the Foundation’s advisory capacity as we work to accelerate progress in understanding and treating […]

Championing Our Cause: How Patients Support Fundraising

By EHE Foundation | August 29, 2023

Join us for EHE Community Connections as we discuss “Championing Our Cause: How Patients Support Fundraising.” Collaborate with other patients and caregivers to explore the most creative and effective fundraising ideas. Together, let’s talk about how to better engage our own community of donors, create awareness and raise money for this one-in-a-million cancer!  This workshop […]

The Pledge: Edition 33, Q2 – April-June, 2023

By EHE Foundation | August 16, 2023

Publication of The Pledge quarterly newsletter is led by the EHE Rare Cancer Charity (UK). EHE patient advocacy groups from around the globe. provide content including research news, patient and fundraising stories, and much more! Click here to view the most recent edition of our online EHE newsletter, The Pledge.

July is Sarcoma Awareness Month – Support Our Mission With a Monthly Donation

By EHE Foundation | July 19, 2023

As we spread sarcoma awareness this month, we ask you to consider a monthly donation. A recurring donation creates a BIG impact in a rare sarcoma, like EHE. We’ve set a goal of 10 new monthly donors! Will you join our Circle of Friends? It’s very affordable and connects you to our small, but mighty […]