EHE Library

The EHE library includes publications and articles about EHE research and treatments, as well as other relevant topics that are available online. Some articles are free with open access and others require subscription.

If you have an article to add or any questions, please contact us at [email protected].

Latest Publications

Featured Article

Epithelioid hemangioendothelioma, an ultra-rare cancer: a consensus paper from the community of experts
This consensus paper provides key recommendations on the management of epithelioid hemangioendothelioma (EHE). Recommendations followed a consensus meeting of a multidisciplinary group of experts from different institutions from Europe, North America and Asia, as well as representatives from the ESMO Faculty, EURACAN, PAEDCAN, GENTURIS, EHE UK/US patient advocates and SPAEN. Thank you to Dr. Silvia Stacchiotti for her leadership and guidance of this groundbreaking resource!

Title of Article (click on title to link)Publication YearKey Words
The TAZ-CAMTA1 fusion protein promotes tumorigenesis via connective tissue growth factor and Ras-MAPK signaling in epithelioid hemangioendothelioma2022TAZ, CAMTA1, fusion
Aurintricarboxylic acid is a canonical disruptor of the TAZ-TEAD transcriptional complex2022YAP, TAZ, TEAD
Primary Intranodal Epithelioid Hemangioendothelioma with Molecular Confirmation2022fusion, CAMTA1
The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer2022YAP, TAZ, TEAD
MRI appearances of hepatic epithelioid hemangioendothelioma: a retrospective study of 57 patients2022liver, hepatic, radiology
Advanced epithelioid hemangioendothelioma of the liver: could lenvatinib offer a bridge treatment to liver transplantation?2022liver, treatment
Primary Pleural Hemangioendothelioma: A Case Report and Literature Review2021pleura, case report
An unusual case of aggressive malignant spread of epithelioid hemangioendothelioma2021case report, bone, aggressive
Primary epithelioid hemangioendothelioma of the penis: a case report and literature review2021case report, penis
Intravenous Ketorolac Infusion for Intractable Pleuritic Pain Secondary to Metastatic Epithelioid Hemangioendothelioma2021pleura, treatment
YAP1-TFE3-fused hemangioendothelioma: a multi-institutional clinicopathologic study of 24 genetically-confirmed cases2021fusion, YAP
Loss of expression of YAP1 C-terminus as an ancillary marker for epithelioid hemangioendothelioma variant with YAP1-TFE3 fusion and other YAP1-related vascular neoplasms2021fusion, YAP
WWTR1(TAZ)-CAMTA1 reprograms endothelial cells to drive epithelioid hemangioendothelioma2021fusion, TAZ, CAMTA1
P10015/SARC033: A phase 2 trial of trametinib in patients with advanced epithelioid hemangioendothelioma (EHE)2021clinical trial
The heterogeneity of Epithelioid Hemangioendothelioma (EHE): A case series and review of the literature with emphasis on treatment options2021hepatic, treatment
Supportive care needs of patients living with an extremely rare and unpredictable cancer: The Epithelioid Haemangioendothelioma patient experience2021symptoms
WWTR1(TAZ)-CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis2021fusion, YAP, TAZ, CAMTA1
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex2021fusion, YAP, TAZ, CAMTA1
Systemic therapies in advanced epithelioid haemangioendothelioma: A retrospective international case series from the World Sarcoma Network and a review of literature2021treatment
Post-resection prognosis of patients with hepatic epithelioid hemangioendothelioma2021liver, hepatic, resection, surgery
Epithelioid hemangioendothelioma, an ultra-rare cancer: a consensus paper from the community of experts2021diagnosis, treatment, survival
Epithelioid hemangioendothelioma of bone: A survival analysis of 50 cases from the SEER database (1992–2016)2021bone, survival
Epithelioid Hemangioendothelioma and Epithelioid Hemangioma: Pazopanib as a Potential Salvage Therapy2021bone, treatment
Clinical prognostic factors in advanced epithelioid haemangioendothelioma: a retrospective case series analysis within the Italian Rare Cancers Network2021survival, prognosis
Loss of expression of YAP1 C-terminus as an ancillary marker for epithelioid hemangioendothelioma variant with YAP1-TFE3 fusion and other YAP1-related vascular neoplasmss2021fusion, YAP
Primary intraoral epithelioid hemangioendothelioma of the tongue: a case report and review of literature2021case report
Primary Bone Marrow Epithelioid Hemangioendothelioma Treated With Gemcitabine and Docetaxel2021bone, treatment
A Case of Pulmonary Epithelioid Hemangioendothelioma with Literature Review2020pulmonary, treatment
Variant WWTR1 gene fusions in epithelioid hemangioendothelioma—A genetic subset associated with cardiac involvement2020fusion
Treatment of Hepatic Epithelioid Hemangioendothelioma2020liver, heptaic, treatment
TAZ-CAMTA1 and YAP-TFE3 modulate the basal TAZ/YAP transcriptional program by recruiting the ATAC histone acetyltransferase complex2020fusion, YAP, TAZ, CAMTA1
Systemic therapies in advanced epithelioid haemangioendothelioma (EHE): A retrospective international series from the World Sarcoma Network2020treatment
Soft‐tissue sarcoma in adults: An update on the current state of histiotype‐specific management in an era of personalized medicine2020treatment, diagnosis
Sirolimus for patients with progressive epithelioid hemangioendothelioma2020treatment
Prognostic Stratification of Clinical and Molecular Epithelioid Hemangioendothelioma Subsets 2020survival, prognosis
Modulation of YAP/ TAZ by statins to improve survival in epithelioid hemangioendothelioma (EHE).2020YAP, TAZ, survival, statin
Health-related quality of life and symptom burden of epithelioid hemangioendothelioma patients: a global patient-driven Facebook study in a very rare malignancy2020symptoms
Childhood Soft Tissue Sarcoma Treatment2020treatment, pediatric
Activity of sirolimus in patients with progressive epithelioid hemangioendothelioma: A case‐series analysis within the Italian Rare Cancer Network2020treatment
1655P Immune signature and molecular profiling of epithelioid hemangioendothelioma2020diagnosis
Effective combined therapy for pulmonary epithelioid hemangioendothelioma: A case report2020pulmonary, treatment
The Role of Local Therapy in Multi-focal Epithelioid Haemangioendothelioma2019treatment, surgery, ablation
Reconstruction of a Thoracic Spine Epithelioid Hemangioendothelioma with Antibiotic Impregnated Poly-methyl Methacrylate: A Case Report2019bone, spine
Imaging findings in epithelioid hemangioendothelioma2019pediatric, radiology
Ga-DOTA-E-[c(RGDfK)]2 positron emission tomography-computed tomography in the evaluation of hepatic hemangioendothelioma epithelioid.2019liver, hepatic, PET
Epithelioid hemangioendothelioma of the bone: A case report with findings of bone scintigraphy2019bone
Common Secondary Genomic Variants Associated With Advanced Epithelioid Hemangioendothelioma2019fusion, CAMTA1
Metastatic Hepatic Epithelioid Hemangioendothelioma Treated with Olaratumab: A Falling Star Rising?2019treatment
Unicentric epithelioid hemangioendothelioma of the calcaneus: a case report and review of literature.2018bone
The Feature of Solitary Small Nodular Type of Hepatic Epithelioid Hemangioendothelioma.2018liver, hepatic
Small, incidental hepatic epithelioid haemangioendothelioma the role of ablative therapy in borderline patients.2018liver, hepatic, ablation
Hepatic Epithelioid Hemangioendothelioma Presenting as an Enlarging Vascular Lesion within the Spleen.2018liver, hepatic
Diffuse hepatic epithelioid hemangioendothelioma with multiple splenic metastasis and delayed multifocal bone metastasis after liver transplantation on FDG PET/CT images: A case report2018liver, transplant, hepatic, PET
Clinical characteristics of Japanese patients with epithelioid hemangioendothelioma: a multicenter retrospective study.2018treatment, prognosis
An Aggressive Large Epithelioid Hemangioendothelioma of the Anterior Mediastinum in a Young Woman2018resection, surgery
A Case of Vanishing Metastatic Mass: Right Atrial Mass in the Setting of Primary Epithelioid Hemangioendothelioma of the Spine.2018bone, spine
Epithelioid Hemangioendothelioma: Update on Diagnosis and Treatment2018treatment
Epithelioid Hemangioendothelioma as a Model of YAP/TAZ-Driven Cancer: Insights from a Rare Fusion Sarcoma2018fusion, YAP, TAZ
New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports.2017lung, pulmonary
F-FDG PET/CT in Pleural Epithelioid Hemangioendothelioma.2017lung, pleura, pulmonary, PET
Epithelioid hemangioendothelioma of the spine: case report and review of the literature.2017bone, spine
Epithelioid hemangioendothelioma of the craniocervical junction; case report and review2017bone, spine
Clinico-radiological features and next generation sequencing of pulmonary epithelioid hemangioendothelioma: A case report and review of literature.2017lung, pulmonary
Hepatic Epithelioid Hemangioendothelioma and Adult Liver Transplantation Proposal for a Prognostic Score Based on the Analysis of the ELTR-ELITA Registry2017liver, hepatic, transplant, treatment
The clinical features of epithelioid hemangioendothelioma in a Han Chinese population: A retrospective analysis2017retrospective
Nuclear Expression of CAMTA1 Distinguishes Epithelioid Hemangioendothelioma From Histologic Mimics2016CAMTA1, fusion
Pazopanib in advanced vascular sarcomas: an EORTC Soft Tissue and Bone Sarcoma Group (STBSG) retrospective analysis2016treatment, retrospective
Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein2016fusion, TAZ, CAMTA1
Long term follow up after resection emphasizes the role of surgery in Primary Hepatic Epithelioid Hemangioendothelioma 2016liver, hepatic, resection, surgery
Epithelioid hemangioendotheliomas with TFE3 gene translocations are compossible with CAMTA1 gene rearrangements2016fusion, YAP, CAMTA1
Mediastinal Epithelioid Hemangioendothelioma2016case report
Unraveling the Mysteries of Epithelioid Hemangioendothelioma: A Conversation with Dr. Brian Rubin2015fusion
Pulmonary Epithelioid Hemangioendothelioma: Advances in Treatment Options Despite a Rare Vascular Tumor2015lung, pulmonary, treatment
Epithelioid hemangioendothelioma of the spine treated with RapidArc volumetric-modulated radiotherapy2014spine, treatment
Pazopanib for metastatic pulmonary epithelioid hemangioendothelioma-a suitable treatment option: case report and review of anti-angiogenic treatment options.2014lung, pulmonary, treatment
Long-term durable response to lenalidomide in a patient with hepatic epithelioid hemangioendothelioma2014liver, hepatic, treatment
Epithelioid Hemangioendothelioma: clinicopathologic, immunhistochemical, and molecular genetic analysis of 39 cases2014fusion, YAP, TAZ, diagnosis
Epithelioid hemangioendothelioma: an overview and update on a rare vascular tumor2014diagnosis, treatment, survival, symptoms
Epithelioid hemangioendothelioma of the liver as a rare indication for liver transplantation.2014liver, transplant, hepatic
Clinicopathological characteristics of pulmonary epithelioid hemangioendothelioma: A report of four cases and review of the literature2014lung, pulmonary
Cervical spine epithelioid hemangioendothelioma: case report2014bone, spine
A Multidisciplinary Approach to the Management of Atypical Osseous Epithelioid Hemangioendothelioma2014bone, treatment
Treatment sequencing strategy for hepatic epithelioid haemangioendothelioma2013liver, hepatic, treatment
Treatment of pulmonary epithelioid hemangioendothelioma with combination chemotherapy: Report of three cases and review of the literature2013lung, pulmonary, treatment,
Sorafenib in patients with progressive epithelioid hemangioendothelioma: a phase 2 study by the French Sarcoma Group (GSF/GETO)2013clinical trial
Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma2013fusion, YAP
Hepatic Epithelioid Hemangioendothelioma Treated With Irreversible Electroporation and Antibiotics2013liver, heptatic, treatment, IRE
An open-label, multicenter, phase II study of bevacizumab for the treatment of angiosarcoma and epithelioid hemangioendotheliomas2013clinical trial
Metastatic Pulmonary Epithelioid Hemangioendothelioma: A case report and review of the literature2012lung, pulmonary
Activity of Angiogenesis Inhibitors in Metastatic Epithelioid Hemangioendothelioma: A Case Report2012bone
Primary Pulmonary Epithelioid Hemangioendothelioma: A Rare Cause of PET-Negative Pulmonary Nodules2011lung, pulmonary, PET
Multicentric Epithelioid Hemangioendothelioma Involving the Same Lower Extremity: A Case Report and Review of Literature2011bone
Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma2011fusion
Clinical patterns and outcome in epithelioid hemangioendothelioma with or without pulmonary involvement: insights from an internet registry in the study of a rare cancer2011lung, pulmonary
A novel WWTR1-CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites.2011fusion, CAMTA1
Vascular endothelial growth factor expression in hepatic epithelioid hemangioendothelioma: Implications for treatment and surgical management2010liver, transplant, hepatic, treatment
Successful treatment of metastatic hepatic epithelioid hemangioendothelioma with thalidomide: a case report2010liver, hepatic, treatment
Primary pleural epithelioid hemangioendothelioma (EHE) – two cases and review of the literature2010lung, pleura, pulmonary
Liver transplantation and vascular tumours.2010liver, transplant, hepatic
Inhibiting the VEGF-VEGFR pathway in angiosarcoma, epithelioid hemangioendothelioma, and hemangiopericytoma/solitary fibrous tumor2010VEGF
Hepatic epithelioid haemangioendothelioma: is transplantation the only treatment option?2010liver, transplant, hepatic, treatment
Treatment of Hepatic Epithelioid Hemangioendothelioma A Single-Institution Experience With 25 Cases2009liver, hepatic, treatment, retrospective
Liver transplantation for hepatic epithelioid hemangioendothelioma: the Canadian multicentre experience.2008liver, hepatic
Epithelioid Hemangioendothelioma of the Head and Neck: Role of Podoplanin in the Differential Diagnosis2007treatment
The place of liver transplantation in the treatment of hepatic epitheloid hemangioendothelioma: report of the European liver transplant registry2007liver, hepatic, transplant
Primary malignant hepatic epithelioid hemangioendothelioma A comprehensive review of the literature with emphasis on the surgical therapy2006liver, hepatic, transplant, surgery
Management of hepatic epithelioid haemangioendothelioma in children: what option?2004liver, hepatic, pediatric
Vascular tumors of bone: A study of 17 cases other than ordinary hemangioma, with an evaluation of the relationship of hemangioendothelioma of bone to epithelioid hemangioma, epithelioid hemangioendothelioma, and high-grade angiosarcoma2003bone
Hepatic epithelioid hemangioendothelioma: resection or transplantation, which and when?1999liver, transplant, hepatic, resection, surgery
Long Term Results Following Liver Transplantation For Primary Hepatic Epithelioid Hemangioendothelioma1995liver, transplant, hepatic, survival
Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma1982diagnosis
Towards a Proper Diagnosis and Understanding of Epitheliod Hemangioendotheliomafusion, CAMTA1, diagnosis