One-in-a-million people are living with EHE worldwide.

Our mission is to find treatments and a cure for epithelioid hemangioendothelioma (EHE) by advancing research and driving collaboration among patients, researchers, and clinicians.

We envision a world where Epithelioid Hemangioendothelioma (EHE) is easily diagnosed and treatable. Join our dedicated community by subscribing to our emails.

With the generosity, heart, and determination of the EHE community and the EHE Foundation Board of Directors, we raised more than $155,000 — and counting — for EHE Research this Giving Tuesday! In a world with so many urgent needs, we are profoundly grateful for how this community continues to show up for one another to advance our mission of finding treatments and a cure for EHE. Thank you!

Patient-Powered EHE Research

EHE Biobank

Patients are the key to finding new treatments for EHE! Researchers need tumor tissue and fluid from EHE patients to understand disease progression and speed the development of new drugs and therapies.

Patient-Powered EHE Research

EHE Global Patient Registry

The EHE Global Patient Registry empowers people with Epithelioid Hemangioendothelioma (EHE) to join together to improve our understanding of this ultra-rare sarcoma. We need every EHE patient to join this critical tool used to support researchers searching for treatments and a cure for EHE.

Latest EHE News, Events and Research

EHE Researchers at YAP/TAZ and TEADs Conference in Telluride, CO

Advancing EHE Research at the 9th Annual YAP/TAZ and TEADs Workshop in Telluride, Colorado

By EHE Foundation | July 17, 2025

The 9th Annual YAP/TAZ and TEADs: At the Crossroads of Cancer workshop took place June 9-13, 2025, in the stunning mountain town of Telluride, Colorado. Hosted by the Telluride Science and Innovation Center and organized by Drs. Guy Weinberg and John Lamar, this unique gathering brought together top-tier researchers and clinicians from academia and industry […]

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Sarah McMullan

Supporting the Next Generation of EHE Researchers: Sarah McMullan of the Lamar Lab Attends International YAP/TAZ Workshop

By EHE Foundation | July 15, 2025

The EHE Foundation is proud to support the next generation of scientists working to unlock the mysteries of epithelioid hemangioendothelioma (EHE). Recognizing the importance of academic and scientific conferences, the Foundation provides annual support to help young investigators overcome financial barriers that might otherwise prevent them from attending these crucial events. A 2025 Fellowship Travel […]

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2025 EHE Fun Run & Walk

2025 EHE Fun Run & Walk Raises More Than $90,000 for EHE Research!

By EHE Foundation | July 11, 2025

This Spring, the EHE community showed up stronger than ever for the 2025 EHE Fun Run & Walk, raising an astounding $90,000+ to fund research aimed at improving outcomes in epithelioid hemangioendothelioma (EHE). This marks a record-breaking year for our signature awareness and fundraising event! Each year, the Fun Run & Walk brings together patients, […]

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The Pledge: Edition 40 - January-March, 2025

The Pledge: Edition 40, Q1 – January-March, 2025

By EHE Foundation | June 16, 2025

Publication of The Pledge quarterly newsletter is led by the EHE Rare Cancer Charity (UK). EHE patient advocacy groups from around the globe provide content including research news, patient and fundraising stories, and much more. Click here to view the most recent edition of the online EHE newsletter, The Pledge.

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ASCO 2025 Recap

ASCO 2025 Recap: Advancing Research to Conquer Cancer

By EHE Foundation | June 8, 2025

Denise Robinson, EHE Foundation Executive Director and Director of Research, had the privilege of representing the Foundation at the 2025 ASCO Annual Meeting in Chicago, where tens of thousands of global oncology professionals gathered to share knowledge with a purposeful commitment to conquer cancer.  The American Society of Clinical Oncology (ASCO) is the world’s leading […]

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The EHE Foundation Welcomes Two New Board Members

The EHE Foundation Welcomes Two New Board Members

By EHE Foundation | June 5, 2025

The EHE Foundation is proud to announce the addition of two new members to our Board of Directors: Hollace D. Leppert, DO, FACOI, and Krista Sheeley, BSN, RN. Both bring extensive healthcare experience, leadership, and passion to our mission. We are excited to welcome them to the EHE Foundation and look forward to their insight, […]

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Translating molecular mechanisms of EHE to improve patient outcomes

Translating molecular mechanisms of EHE to improve patient outcomes

By EHE Foundation | December 17, 2025

Scientists know that most EHE tumors are caused by specific genetic changes called gene fusions. In most people with EHE, two genes, WWTR1 and CAMTA1, are abnormally fused. In a smaller number of cases, a different fusion involving YAP1 and TFE3 is present. In a recent review published in Critical Reviews in Oncology/Hematology, the authors […]

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EHE in Canada: what a national study tells us

EHE in Canada: what a national study tells us

By EHE Foundation | December 17, 2025

A recent study published in the European Journal of Cancer represents the largest collection of data from people with EHE in Canada. Researchers found that EHE can behave very differently from person to person—about one-third of patients were diagnosed by chance and did not need immediate treatment, while others had more aggressive disease. About half […]

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Pulmonary EHE: a case report and review of literature

Pulmonary EHE: a case report and review of literature

By EHE Foundation | December 17, 2025

In a recent issue of AME Case Reports, a team led by Dr. Clifford Atuiri describes a case of pulmonary epithelioid hemangioendothelioma (EHE) and places it within the broader understanding of the disease. The authors note that EHE in the lungs can be difficult to diagnose because symptoms and imaging often resemble more common lung […]

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