One-in-a-million people are living with EHE worldwide.

Our mission is to find treatments and a cure for this rare cancer by advancing research and driving collaboration between patients, researchers, and clinicians.

We envision a world where Epithelioid Hemangioendothelioma (EHE) is easily diagnosed and treatable. Join our dedicated community by subscribing to our emails.

Together, WE GAVE!

Our Giving Tuesday total is a staggering $183,737 and counting! That's $87,237 in community donations and $96,500 contributed by our Board of Directors.

Let’s keep this momentum going! If you haven’t donated yet, it’s not too late—every dollar makes a difference.

We are overwhelmed with gratitude—not just for your incredible support on #GivingTuesday, but for standing with us every single day.

Join us for EHE 360 Connect on Monday, February 24, 2025, 12:00-1:00 pm ET. This webinar features Dr. Scott M. Schuetze, University of Michigan, Rogel Cancer Center, presenting "Results of a Phase 2 Trial of Trametinib in Advanced EHE."

Patient-Powered EHE Research

EHE Biobank

Patients are the key to finding new treatments for EHE! Researchers need tumor tissue and fluid from EHE patients to understand disease progression and speed the development of new drugs and therapies.

EHE Global Patient Registry

The EHE Global Patient Registry empowers people with Epithelioid Hemangioendothelioma (EHE) to join together to improve our understanding of this ultra-rare sarcoma. We need every EHE patient to join this critical tool used to support researchers searching for treatments and a cure for EHE.

EMPOWER YOURSELF WITH KNOWLEDGE

Upcoming Foundation Events

Consensus Paper on EHE Management

The Consensus Paper is a powerful, EHE-specific resource for patients, caregivers, and medical professionals that answers critical questions regarding diagnosis and treatment. Patients are encouraged to read it to better understand EHE and facilitate more informed discussions and decision-making with medical teams.

Latest EHE News, Events and Research

CTOS 2024 Highlights

Highlights from CTOS 2024

By The EHE Foundation | December 30, 2024

In November, Denise Robinson, Executive Director and Director of Research attended the CTOS 2024 Annual Meeting in San Diego, CA. The Connective Tissue Oncology Society (CTOS), is a professional medical organization that brings together multi-disciplinary clinician-scientists, translational researchers, and advocates from all over the world to advance the treatment of sarcomas. Many of the world’s […]

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The Pledge: Edition 38, Q3 – July-September, 2024

The Pledge: Edition 38, Q3 – July-September, 2024

By The EHE Foundation | November 21, 2024

Publication of The Pledge quarterly newsletter is led by the EHE Rare Cancer Charity (UK). EHE patient advocacy groups from around the globe. provide content including research news, patient and fundraising stories, and much more. Click here to view the most recent edition of our online EHE newsletter, The Pledge.

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2024 Research Grant Awards

The EHE Foundation Announces Grant Funding of $307,400 to Advance Research and Find Treatments for EHE

By The EHE Foundation | November 20, 2024

We are pleased to announce The EHE Foundation’s 2024 Research Grants Program awards, totaling $307,400, as part of our ongoing commitment to advance our mission to find effective treatments and a cure for EHE. Made possible by 2023 Giving Tuesday gifts, these grants support novel translational research projects that aim to identify and accelerate the […]

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Donating vs. Fundraising

Making a Donation vs. Fundraising for The EHE Foundation: What’s the Difference?

By The EHE Foundation | November 4, 2024

At The EHE Foundation, we are committed to finding a cure for epithelioid hemangioendothelioma (EHE), an ultra-rare and potentially aggressive cancer that affects one in a million people. Every contribution helps us advance groundbreaking research, support patients, and foster collaboration among clinicians and researchers worldwide. There are two impactful ways you can support our mission: […]

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EHEF Scientific & Medical Advisory Board

Scientific & Medical Advisory Board Collaborates to Improve Outcomes for People Living with EHE

By The EHE Foundation | September 30, 2024

On September 10, 2024, The EHE Foundation held a virtual meeting of our Scientific & Medical Advisory Board (SMAB). The meeting aimed to welcome new members, review current research projects, and discuss future needs and goals to advance EHE research. The meeting began with a warm welcome to new members of the SMAB: Tom Chen, […]

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test tubes

GDF-15 Predicts Epithelioid Hemangioendothelioma Aggressiveness and is Down-regulated by Sirolimus Through ATF4/ATF5 Suppression

By The EHE Foundation | September 27, 2024

Drs. Silvia Stacchiotti, Sandro Pasquali, and Nadia Zaffaroni (IRCCS – INT, Milan, Italy) and colleagues published their promising findings in Clinical Cancer Research, September 16, 2024. This study, funded in part by The EHE Foundation in partnership with EHE Rare Cancer Charity (UK), aimed to assess the efficacy of sirolimus for the treatment of EHE […]

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Brian Frank

A Day of Fun Celebrating the Life of Brian Frank

By The EHE Foundation | August 10, 2018

Brian Frank passed away from EHE on September 2, 2014 at the age of 28. Brian had only been sick for about 6 months and was not properly diagnosed until he passed.  His family and friends, led by his mother, Darlene Frank, and his sister, Angela Osborn, organize an annual event in Brian’s memory, which […]

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Giving Tuesday

Giving Tuesday

By The EHE Foundation | January 2, 2018

Giving Tuesday is celebrated each year on the Tuesday following Thanksgiving and after the widely recognized Black Friday and Cyber Monday.  It is recognized as an international day of giving at the beginning of the holiday season and is fueled by the power of social media. The day known as “#GivingTuesday” proved to be a […]

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EHE cancer The Pledge

Stay up to Date on EHE by Reading The Pledge: 11th Edition

By The EHE Foundation | January 1, 2018

Click here to read the Pledge, 11th Edition

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