One-in-a-million people are living with EHE worldwide.

Our mission is to find treatments and a cure for this rare cancer by advancing research and driving collaboration between patients, researchers, and clinicians.

We envision a world where Epithelioid Hemangioendothelioma (EHE) is easily diagnosed and treatable. Join our dedicated community by subscribing to our emails.

Patient-Powered Research

Patients Powering Research for Epithelioid Hemangioendothelioma

EHE Global Patient Registry

The EHE Global Patient Registry empowers people with Epithelioid Hemangioendothelioma (EHE) to join together to improve our understanding of this ultra-rare sarcoma.

EHE Biobank

Patients are the key to finding new treatments for EHE! Researchers need tumor tissue, blood and fluid from EHE patients to understand disease progression and speed development of new drugs and therapies.

April is EHE Awareness Month

Upcoming Foundation Events

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Patient Services

Whether you are newly diagnosed or have been living with EHE for a while, you are not alone. The EHE Community is stronger together and includes patients, their families and friends and the many specialists working tirelessly to find treatments and a cure. 

Latest EHE News, Events and Research

The Lamar Lab

Funded Research Project Update: Use of pre-clinical EHE models to identify druggable pathways to treat EHE

By The EHE Foundation | September 7, 2023

Investigator: John Lamar, PhD, Albany Medical College Dr. Lamar was awarded a 3-year grant by The EHE Foundation in 2022, that aims to identify FDA-approved drugs that inhibit EHE cell growth, and then test them in pre-clinical mouse models for the treatment of EHE. What does this mean for patients? This could mean a shorter […]

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Ajaybabu Pobbati

Funded Research Project Update: Repurposing an FDA-approved Drug for EHE Treatment

By The EHE Foundation | September 7, 2023

Investigator: Ajaybabu Pobbati, PhD, Cleveland Clinic – Lerner Research Institute In 2022, The EHE Foundation funded a grant to Dr. Pobbati for research that looks at a library of current FDA-approved drugs that act as TAZ-CAMTA1 (TC) or TEAD inhibitors, for use in EHE. What does this mean for patients? This could mean a shorter […]

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EHE Community Connections: Championing Our Cause - How patients drive fundraising support

Championing Our Cause: How Patients Support Fundraising

By The EHE Foundation | August 29, 2023

Join us for EHE Community Connections as we discuss “Championing Our Cause: How Patients Support Fundraising.” Collaborate with other patients and caregivers to explore the most creative and effective fundraising ideas. Together, let’s talk about how to better engage our own community of donors, create awareness and raise money for this one-in-a-million cancer!  This workshop […]

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The Pledge (Q2 2023)

The Pledge: Edition 33, Q2 – April-June, 2023

By The EHE Foundation | August 16, 2023

Publication of The Pledge quarterly newsletter is led by the EHE Rare Cancer Charity (UK). EHE patient advocacy groups from around the globe. provide content including research news, patient and fundraising stories, and much more! Click here to view the most recent edition of our online EHE newsletter, The Pledge.

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Support our mission with a recurring donation.

July is Sarcoma Awareness Month – Support Our Mission With a Monthly Donation

By The EHE Foundation | July 19, 2023

As we spread sarcoma awareness this month, we ask you to consider a monthly donation. A recurring donation creates a BIG impact in a rare sarcoma, like EHE. We’ve set a goal of 10 new monthly donors! Will you join our Circle of Friends? It’s very affordable and connects you to our small, but mighty […]

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TEAD Talk with David Casimir

TEAD Talk – The Pursuit of a Treatment and Cure for EHE

By The EHE Foundation | July 12, 2023

Thanks to David Casimir, PhD, JD, for his informative patient-level presentation on June 17, 2023, that addressed the questions: What is the Hippo pathway and TEAD? How do they relate to EHE? How are they being used to develop EHE treatments? How do these treatments move from the laboratory, through clinical trials, to patient care? […]

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EHE Advocates at the ESMO Congress 2024

EHE Advocates at the ESMO Sarcoma and Rare Cancers Congress 2024

By The EHE Foundation | March 29, 2024

In March Denise Robinson, Director of Research for The EHE Foundation attended the ESMO Sarcoma and Rare Cancers Congres 2024 in Lugano, Switzerland. This congress brought together world-renowned experts including researchers and clinicians, to present and discuss the latest advancements in the treatment of sarcomas and rare cancers.  Topics ranged from the role of immune […]

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PUSH Project: Pushing Rare Sarcoma Beyond Hope

PUSH Project: Pushing Rare Sarcoma Beyond Hope

By The EHE Foundation | March 29, 2024

Under the umbrella of the Connective Tissue Oncology Society (CTOS), the Ultra-rare Sarcoma Working Group, a broad group representing the global sarcoma community, including clinicians, scientists, patient advocates, and non-profit organizations has come together to establish a consortium, PUSH, to collect and make the best use of all available evidence to facilitate the development of […]

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EHE patients' voices inform paper on sirolimus for the treatment of EHE.

EHE patients’ voices inform paper on sirolimus for the treatment of EHE.

By The EHE Foundation | March 15, 2024

“The patient perspective on sirolimus for epithelioid hemangioendothelioma (EHE): results of a community survey highlighting the importance of equitable access to treatments” was published on February 25, 2024, in the scientific journal Frontiers in Oncology. In early 2023, EHE patient advocates surveyed the global EHE community to gain patients’ perspectives on sirolimus to generate information […]

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