People with EHE are

one-in-a-million!

Donations to support EHE cancer research are DOUBLED through Giving Tuesday, December 2, 2025. Give now to DOUBLE your impact!

We envision a world where Epithelioid Hemangioendothelioma (EHE) is easily diagnosed and treatable. Join our dedicated community by subscribing to our emails.

Patient-Powered EHE Research

EHE Biobank

Patients are the key to finding new treatments for EHE! Researchers need tumor tissue and fluid from EHE patients to understand disease progression and speed the development of new drugs and therapies.

Patient-Powered EHE Research

EHE Global Patient Registry

The EHE Global Patient Registry empowers people with Epithelioid Hemangioendothelioma (EHE) to join together to improve our understanding of this ultra-rare sarcoma. We need every EHE patient to join this critical tool used to support researchers searching for treatments and a cure for EHE.

Latest EHE News, Events and Research

EHE Research Roundtable

Research Roundtable: Advocacy in Action

By The EHE Foundation | February 11, 2025

In late January, 2025, EHE advocacy leaders from The EHE Foundation, EHE Rare Cancer Charity UK, and EHE ITALIA Associazione Non Solo LAURA ODV coordinated a joint meeting with expert clinicians and researchers in Amsterdam, The Netherlands. Stakeholders from Italy, the United Kingdom, and the United States reviewed progress on ongoing collaborative research programs and explored key research […]

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CTOS 2024 Highlights

Highlights from CTOS 2024

By The EHE Foundation | December 30, 2024

In November, Denise Robinson, Executive Director and Director of Research attended the CTOS 2024 Annual Meeting in San Diego, CA. The Connective Tissue Oncology Society (CTOS), is a professional medical organization that brings together multi-disciplinary clinician-scientists, translational researchers, and advocates from all over the world to advance the treatment of sarcomas. Many of the world’s […]

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The Pledge: Edition 38, Q3 – July-September, 2024

The Pledge: Edition 38, Q3 – July-September, 2024

By The EHE Foundation | November 21, 2024

Publication of The Pledge quarterly newsletter is led by the EHE Rare Cancer Charity (UK). EHE patient advocacy groups from around the globe. provide content including research news, patient and fundraising stories, and much more. Click here to view the most recent edition of our online EHE newsletter, The Pledge.

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2024 Research Grant Awards

The EHE Foundation Announces Grant Funding of $307,400 to Advance Research and Find Treatments for EHE

By The EHE Foundation | November 20, 2024

We are pleased to announce The EHE Foundation’s 2024 Research Grants Program awards, totaling $307,400, as part of our ongoing commitment to advance our mission to find effective treatments and a cure for EHE. Made possible by 2023 Giving Tuesday gifts, these grants support novel translational research projects that aim to identify and accelerate the […]

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Donating vs. Fundraising

Making a Donation vs. Fundraising for The EHE Foundation: What’s the Difference?

By The EHE Foundation | November 4, 2024

At The EHE Foundation, we are committed to finding a cure for epithelioid hemangioendothelioma (EHE), an ultra-rare and potentially aggressive cancer that affects one in a million people. Every contribution helps us advance groundbreaking research, support patients, and foster collaboration among clinicians and researchers worldwide. There are two impactful ways you can support our mission: […]

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EHEF Scientific & Medical Advisory Board

Scientific & Medical Advisory Board Collaborates to Improve Outcomes for People Living with EHE

By The EHE Foundation | October 1, 2024

On September 10, 2024, The EHE Foundation held a virtual meeting of our Scientific & Medical Advisory Board (SMAB). The meeting aimed to welcome new members, review current research projects, and discuss future needs and goals to advance EHE research. The meeting began with a warm welcome to new members of the SMAB: Tom Chen, […]

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Drs. Claudia Giani and Anna Maria Frezza

EHE Stabilization with Sirolimus: Results From POEM, a Prospective Multicentric Observational Study

By The EHE Foundation | November 6, 2025

Drs. Claudia Giani, Anna Maria Frezza, Silvia Stacchiotti, and colleagues from the Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, and Royal Marsden Hospital, London, UK, presented results from POEM: a prospective observational study on Epithelioid Haemangioendothelioma at ESMO Congress 2025. The data presented included 57 consecutive molecularly confirmed EHE patients who entered the study, […]

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Jason Hanna, PhD from the Hanna Lab at Purdue University

Hanna Lab at Purdue University: ‘When cells in the body stop following the rules, cancer can take hold.’

By The EHE Foundation | October 14, 2025

You met Jason Hanna, PhD, at the 2025 EHE Global Patient Conference, where he highlighted work his lab is undertaking in EHE. We are thrilled to share a recent publication in Molecular Oncology from the Hanna Lab at Purdue University, highlighting their findings from a study focused on the YAP1-TFE3 subtype of EHE.  The YAP1-TFE3 […]

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Tanas Lab at the University of Iowa

Exciting Progress in EHE Research – Powered by Patients

By The EHE Foundation | October 10, 2025

We are thrilled to share a new publication, “EHE cell cultures are a platform for mechanistic and therapeutic investigation,” made possible by a partnership between the University of Iowa and the EHE Foundation. Under the leadership of Dr. Munir Tanas, Nicholas Scalora, PhD, and colleagues in the Tanas Lab sought to develop long-term EHE cell […]

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