One-in-a-million people are living with EHE worldwide.

Our mission is to find treatments and a cure for epithelioid hemangioendothelioma (EHE) by advancing research and driving collaboration among patients, researchers, and clinicians.

We envision a world where Epithelioid Hemangioendothelioma (EHE) is easily diagnosed and treatable. Join our dedicated community by subscribing to our emails.

Patient-Powered EHE Research

EHE Biobank

Patients are the key to finding new treatments for EHE! Researchers need tumor tissue and fluid from EHE patients to understand disease progression and speed the development of new drugs and therapies.

EHE Global Patient Registry

The EHE Global Patient Registry empowers people with Epithelioid Hemangioendothelioma (EHE) to join together to improve our understanding of this ultra-rare sarcoma. We need every EHE patient to join this critical tool used to support researchers searching for treatments and a cure for EHE.

Latest EHE News, Events and Research

The Hershey Company Donates to EHE Research

By EHE Foundation | October 30, 2016

The Hershey Company has made a generous donation to The EHE Foundation. The world-famous confections company in Pennsylvania gave $500 to support ongoing research efforts into the rare cancer. The Foundation would like to thank Hershey employee Serena Wang for the support. Serena was a personal friend of Mandy O’Connor, who died from EHE in […]

Stay up to Date on EHE by Reading The Pledge: Sixth Edition

By EHE Foundation | October 30, 2016

EHE is no longer some unknown rare cancer! The grassroots movement to raise awareness and help fund EHE research is now a worldwide effort! Thanks to Hugh Leonard, director of The EHE Rare Cancer Charity UK, for assembling EHE stories for the sixth edition of The Pledge. Download The Pledge here.

The EHE Foundation Advisory Board

By EHE Foundation | September 26, 2016

Meet the Men & Women Fighting EHE in the Lab

The EHE Foundation Receives $10,000 Donation

By EHE Foundation | September 26, 2016

The Bock Foundation, the philanthropic arm of Ernest Bock & Sons, Inc., a construction and hospitality conglomerate in Pennsylvania, has been making substantial contributions to charitable causes for decades. Back in 1992, a Bock employee was tragically killed in an automobile accident. The Bock family aided in funeral expenses, and quickly realized the organization could […]

1st Annual EHE Virtual 5K Run/Walk

By EHE Foundation | May 26, 2016

This run/walk is an all ages and abilities event for EHE. EHE is short for Epithelioid Hemangioendothelioma, an extremely rare and often deadly vascular sarcoma (cancer) that primarily affects adolescents and young adults. This event is “virtual”, which means it can be done anywhere you are. You can complete the 3.1 miles by running, walking, […]

Fighting with Laughter – The EHE Foundation and The Hope Gala

By EHE Foundation | January 8, 2016

Saturday, January 30, 2016 2:30 PM Gotham Comedy Club – The Vintage Lounge 208 W 23rd St New York, NY 10011 Click here for tickets! Mandy O’Connor, a Penn State graduate and THON participant, fought Epithelioid Hemangioendothelioma (EHE) for more than a decade. EHE is a rare and often deadly vascular sarcoma (cancer) that largely […]

EHE Foundation Awards $335,000 in New Research Grants to Advance Progress in EHE

By EHE Foundation | March 16, 2026

The EHE Foundation is proud to announce $335,000 in funding through the 2026 EHE Foundation Research Grants Program to support two innovative research projects in epithelioid hemangioendothelioma (EHE). Selected for their scientific merit, potential impact, and clinical relevance, these projects address two important priorities in EHE research: biomarker development and new therapeutic approaches. Together, they […]

The Pledge: Edition 43, Q4 – October-December, 2025

By EHE Foundation | February 15, 2026

Publication of The Pledge quarterly newsletter is led by the EHE Rare Cancer Charity (UK). EHE patient advocacy groups from around the globe provide content, including research news, patient and fundraising stories, and much more. Click here to view the most recent edition of the online EHE newsletter, The Pledge.

Understanding Quality of Life for People Living With EHE

By Kristianne Oristian, PhD | February 10, 2026

The European Organisation of Research and Treatment of Cancer (EORTC) is conducting research to better understand health-related quality of life (HRQoL) concerns among people living with rare cancers. Recently, researchers analyzed results from a group of 31 people with EHE from 11 different countries who participated in the study. The findings showed that pain–and the […]